Chemoimmunotherapy of murine mammary adenocarcinomas.

Posttherapy Counter-Regulation Tumors via Persistent Blockade of Cure of Spontaneous Murine Mammary Chronic Chemoimmunotherapy Achieves

Rhopalurus junceus scorpion venom induces antitumor effect in vitro and in vivo against a murine mammary adenocarcinoma model

Objective(s): In Cuba the endemic scorpion species Rhopalurus junceus has been used in traditional medicine for cancer treatment and related diseases. However there is no scientific evidence about its therapeutic potential for cancer treatment. The aim of the study was to determine the antitumor effect of scorpion venom against a murine mammary adenocarcinoma F3II. <br...

Coxsackie and adenovirus receptor promotes adenocarcinoma cell survival and is expressionally activated after transition from preneoplastic precursor lesions to invasive adenocarcinomas.

PURPOSE The cell adhesion protein, coxsackie and adenovirus receptor (CAR), is differentially expressed in various human adenocarcinomas. We analyzed the role of differential CAR expression during tumorigenesis and in cell survival of adenocarcinomas. EXPERIMENTAL DESIGN In a murine mammary cancer model, a syngenic preneoplastic mammary tissue was implanted into the mammary fat pads of syngen...

Factors related to therapeutic efficacy in adoptive chemoimmunotherapy of a Friend virus-induced lymphoma.

Adult C57BL/6 mice given syngeneic Friend lymphoma cells (FBL-3) usually died on Day 12 to 15. Treatment on Day 5 with cyclophosphamide (CY), 180 mg/kg, and lymphoid cells from C57BL/6 mice immunized with FBL-3 cured most mice, whereas cells alone had no effect and CY alone or with nonimmune cells only doubled the median survival time. As an adjunct to CY, at least 3 X IO6 spleen cells or perip...

Primary Stromal Sarcoma of Breast with Nodal Recurrence

  Although most breast cancers are adenocarcinomas of the mammary gland, primary breast sarcomas may also arise from mammary gland mesenchymal tissue. Sarcomas represent less than 1% of primary breast neoplasms. These tumors are at high risk of recurrence and are known to have poor prognosis. Surgical resection is the primary treatment for these lesions and axillary lymph node dissection is no...